Title : Altered expression of tight junction molecules in alveolar septa in lung injury and fibrosis.

Pub. Date : 2012 Jan 15

PMID : 22003091






2 Functional Relationships(s)
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1 In addition, we analyzed the influence of transforming growth factor-beta (TGF-beta), a critical mediator of pulmonary fibrosis that is upregulated after bleomycin-induced lung injury, on tight junctions in vitro. Bleomycin transforming growth factor beta 1 Homo sapiens
2 These results suggest that bleomycin-induced lung injury causes pathogenic alterations in tight junctions and that such alterations seem to be induced by TGF-beta. Bleomycin transforming growth factor beta 1 Homo sapiens