Pub. Date : 2012 Feb
PMID : 22002102
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Wild type p53 function inhibits the efficacy of a combined IR and ABT-737 treatment via a p21-dependent G1 cell cycle arrest. | 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid | tumor protein p53 | Homo sapiens |
| 2 | Moreover, mutant as well as wild type p53 counteract the pro-apoptotic activity of ABT-737 by maintaining the expression levels of the Mcl-1 protein. | 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid | tumor protein p53 | Homo sapiens |
| 3 | Thus, p53 regulates the sensitivity to ABT-737 of glioblastoma cells. | 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid | tumor protein p53 | Homo sapiens |