Title : Inhibitory effects of limonin on six human cytochrome P450 enzymes and P-glycoprotein in vitro.

Pub. Date : 2011 Dec

PMID : 22001672






1 Functional Relationships(s)
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1 However, potent inhibition of CYP3A4 by limonin is observed with IC50 values of 6.20 muM (CYP3A4/testosterone) and 19.10 muM (CYP3A4/midazolam). Testosterone cytochrome P450 family 3 subfamily A member 4 Homo sapiens