Pub. Date : 2011 Dec 1
PMID : 22001088
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The de-guanidinylated derivative of peramivir remains a potent inhibitor of influenza neuraminidase. | peramivir | neuraminidase 1 | Homo sapiens |
| 2 | The guanidine function in the potent neuraminidase inhibitor peramivir was included early on in the drug design process, and examination of X-ray structural data for the enzyme-inhibitor complex would seem to indicate that the guanidine plays a critical role in promoting binding. | peramivir | neuraminidase 1 | Homo sapiens |