Title : Endoplasmic reticulum stress and glycogen synthase kinase-3β activation in apolipoprotein E-deficient mouse models of accelerated atherosclerosis.

Pub. Date : 2012 Jan

PMID : 21998135






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A subset of mice from each group was supplemented with sodium valproate (625 mg/kg), a compound with GSK3 inhibitory activity. Valproic Acid glycogen synthase kinase 3 beta Mus musculus
2 Valproate supplementation blocked GSK3beta activation and attenuated the development of atherosclerosis and the accumulation of hepatic lipids in each of the models examined. Valproic Acid glycogen synthase kinase 3 beta Mus musculus