Title : Comparative study on saponin fractions from Panax notoginseng inhibiting inflammation-induced endothelial adhesion molecule expression and monocyte adhesion.

Pub. Date : 2011 Oct 13

PMID : 21995855






4 Functional Relationships(s)
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1 RESULTS: Three saponin fractions and two individual ginsenosides exhibited the inhibitory effects on monocyte adhesion on TNF-alpha-activated HCAECs and expression of ICAM-1 and VCAM-1 at both mRNA and protein levels in vitro. Saponins tumor necrosis factor Homo sapiens
2 These inhibitory effect of saponin fractions maybe attribute partially to the suppression of the TNF-alpha-induced NF-kappaB activation. Saponins tumor necrosis factor Homo sapiens
3 Among the tested saponin fractions, PDS is the most potent saponin fraction against TNF-alpha-induced monocyte adhesion as well as the expression of adhesion molecules in vitro and in vivo. Saponins tumor necrosis factor Homo sapiens
4 Among the tested saponin fractions, PDS is the most potent saponin fraction against TNF-alpha-induced monocyte adhesion as well as the expression of adhesion molecules in vitro and in vivo. Saponins tumor necrosis factor Homo sapiens