Title : Imatinib inhibits proliferation of human mesenchymal stem cells and promotes early but not late osteoblast differentiation in vitro.

Pub. Date : 2012 Jan

PMID : 21993629






2 Functional Relationships(s)
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1 When we measured the relative mRNA expression levels of Runx2, we found that Runx2 expression was higher in imatinib-treated (5 muM) cultures at early time points during differentiation. Imatinib Mesylate latexin Homo sapiens
2 On the other hand, the expression of Osterix late during differentiation was lower in imatinib-treated (5 muM) cultures, corresponding to the ARS results. Imatinib Mesylate latexin Homo sapiens