Title : Development and validation of a method using supported liquid extraction for the simultaneous determination of midazolam and 1'-hydroxy-midazolam in human plasma by liquid chromatography with tandem mass spectrometry detection.

Pub. Date : 2012 Jan 25

PMID : 21993197






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The metabolic conversion of midazolam (MDZ) to its main metabolite 1"-hydroxy-midazolam (1-OH-MDZ) can be used as a probe drug for cytochrome P450 3A (CYP3A) activity. 1-hydroxymethylmidazolam cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 The metabolic conversion of midazolam (MDZ) to its main metabolite 1"-hydroxy-midazolam (1-OH-MDZ) can be used as a probe drug for cytochrome P450 3A (CYP3A) activity. 1-hydroxymethylmidazolam cytochrome P450 family 3 subfamily A member 4 Homo sapiens
3 The metabolic conversion of midazolam (MDZ) to its main metabolite 1"-hydroxy-midazolam (1-OH-MDZ) can be used as a probe drug for cytochrome P450 3A (CYP3A) activity. 1-hydroxymethylmidazolam cytochrome P450 family 3 subfamily A member 4 Homo sapiens
4 The metabolic conversion of midazolam (MDZ) to its main metabolite 1"-hydroxy-midazolam (1-OH-MDZ) can be used as a probe drug for cytochrome P450 3A (CYP3A) activity. 1-hydroxymethylmidazolam cytochrome P450 family 3 subfamily A member 4 Homo sapiens