Pub. Date : 2012 Jun
PMID : 21975431
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The aim of this study was to investigate the methylation status of CpG sites in the MCP-1 promoter in Type 2 diabetic patients and its correlation to serum MCP- 1 level, and blood glucose level. | Glucose | C-C motif chemokine ligand 2 | Homo sapiens |
| 2 | MCP-1 promoter methylation was significantly correlated to serum MCP-1, HbA1c, fasting blood glucose, and triglyceride. | Glucose | C-C motif chemokine ligand 2 | Homo sapiens |
| 3 | CONCLUSION: These data suggest that hypomethylation of CpG sites in the MCP-1 promoter region may be affected by blood glucose and TG, which then increase the serum MCP-1 level and may play a role in the vascular complications of Type 2 diabetes. | Glucose | C-C motif chemokine ligand 2 | Homo sapiens |
| 4 | CONCLUSION: These data suggest that hypomethylation of CpG sites in the MCP-1 promoter region may be affected by blood glucose and TG, which then increase the serum MCP-1 level and may play a role in the vascular complications of Type 2 diabetes. | Glucose | C-C motif chemokine ligand 2 | Homo sapiens |