Pub. Date : 2011 Dec 31
PMID : 21971413
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rottlerin enhances IL-1beta-induced COX-2 expression through sustained p38 MAPK activation in MDA-MB-231 human breast cancer cells. | rottlerin | interleukin 1 beta | Homo sapiens |
| 2 | In this study, we investigated the underlying molecular mechanism of the synergistic effect of rottlerin on interleukin1beta (IL-1beta)-induced COX-2 expression in MDA-MB-231 human breast cancer cell line. | rottlerin | interleukin 1 beta | Homo sapiens |
| 3 | In this study, we investigated the underlying molecular mechanism of the synergistic effect of rottlerin on interleukin1beta (IL-1beta)-induced COX-2 expression in MDA-MB-231 human breast cancer cell line. | rottlerin | interleukin 1 beta | Homo sapiens |
| 4 | Treatment with rottlerin enhanced IL-1beta-induced COX-2 expression at both the protein and mRNA levels. | rottlerin | interleukin 1 beta | Homo sapiens |
| 5 | Taken together, our results suggest that rottlerin causes IL-1beta-induced COX-2 upregulation through sustained p38 MAPK activation in MDA-MB-231 human breast cancer cells. | rottlerin | interleukin 1 beta | Homo sapiens |