Title : Boswellic acids extract attenuates pulmonary fibrosis induced by bleomycin and oxidative stress from gamma irradiation in rats.

Pub. Date : 2011 Sep 30

PMID : 21961991






3 Functional Relationships(s)
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1 This study aims to test the inhibition of 5-lipooxygenase (5-LOX) by boswellic acid (BA) extract in an experimental model of pulmonary fibrosis using bleomycin (BL). boswellic acid lysyl oxidase Rattus norvegicus
2 This study aims to test the inhibition of 5-lipooxygenase (5-LOX) by boswellic acid (BA) extract in an experimental model of pulmonary fibrosis using bleomycin (BL). boswellic acid lysyl oxidase Rattus norvegicus
3 BA extract inhibited the TGF-ss induced fibrosis (P = 0.01) and 5-LOX activity levels (P = 0.005).Histologically, BA reduced the number of infiltrating cells, ameliorated the destruction of lung architecture and attenuated lung fibrosis. boswellic acid lysyl oxidase Rattus norvegicus