Title : Novel natural product-based cinnamates and their thio and thiono analogs as potent inhibitors of cell adhesion molecules on human endothelial cells.

Pub. Date : 2011 Nov

PMID : 21955679






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In the present study, we report the design and synthesis of novel analogs of cinnamates, thiocinnamates and thionocinnamates and evaluated the potencies of these analogs to inhibit TNF-alpha induced ICAM-1 expression on human endothelial cells. Cinnamates tumor necrosis factor Homo sapiens