Title : Leptin boosts cellular metabolism by activating AMPK and the sirtuins to reduce tau phosphorylation and β-amyloid in neurons.

Pub. Date : 2011 Oct 14

PMID : 21945934






1 Functional Relationships(s)
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1 Additionally, the ability of Leptin to reduce tau phosphorylation and beta-amyloid production was sensitive to the AMPK and sirtuin inhibitors, compound C and nicotinamide, respectively. Niacinamide protein kinase AMP-activated non-catalytic subunit beta 1 Homo sapiens