Title : Hemorrhagic shock activation of NLRP3 inflammasome in lung endothelial cells.

Pub. Date : 2011 Nov 1

PMID : 21940680






1 Functional Relationships(s)
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1 In turn, reactive oxygen species derived from NAD(P)H oxidase promote the association of thioredoxin-interacting protein with the nucleotide-binding oligomerization domain-like receptor protein NLRP3 and subsequently induce inflammasome activation and IL-1beta secretion from the EC. Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens