Title : Influence of lactic acid on endogenous and viral RNA-induced immune mediator production by vaginal epithelial cells.

Pub. Date : 2011 Oct

PMID : 21934447






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Poly (inosinic acid:cytidylic acid) by itself stimulated the release of IL-6 (305 pg/mL) and enhanced IL-8 production (2.8 ng/mL). Poly I C-X-C motif chemokine ligand 8 Homo sapiens
2 The combination of poly (inosinic acid:cytidylic acid) and lactic acid markedly increased IL-8 production (5.0 ng/mL) and induced the release of IL-1beta (96.2 pg/mL). Poly I C-X-C motif chemokine ligand 8 Homo sapiens
3 The poly (inosinic acid:cytidylic acid)-mediated lactic acid effect on IL-1beta and IL-8 release was abrogated when the lactic acid was neutralized or if acetic acid was substituted for lactic acid. Poly I C-X-C motif chemokine ligand 8 Homo sapiens