Title : Substitution of the human αC region with the analogous chicken domain generates a fibrinogen with severely impaired lateral aggregation: fibrin monomers assemble into protofibrils but protofibrils do not assemble into fibers.

Pub. Date : 2011 Oct 25

PMID : 21932842






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Plasmin digests of HC fibrinogen produced fragments that were similar to normal D and E; further, as with normal fibrinogen, the knob "A" peptide, GPRP, reversed the plasmin cleavage associated with addition of EDTA. Edetic Acid fibrinogen beta chain Homo sapiens