Title : All-trans retinoic acid promotes TGF-β-induced Tregs via histone modification but not DNA demethylation on Foxp3 gene locus.

Pub. Date : 2011

PMID : 21931768






2 Functional Relationships(s)
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1 Conversely, atRA markedly increased ERK1/2 activation, and blockade of ERK1/2 signaling completely abolished the enhanced effects of atRA on Foxp3 expression. Tretinoin mitogen-activated protein kinase 3 Mus musculus
2 Conversely, atRA markedly increased ERK1/2 activation, and blockade of ERK1/2 signaling completely abolished the enhanced effects of atRA on Foxp3 expression. Tretinoin mitogen-activated protein kinase 3 Mus musculus