Title : The hedgehog receptor patched is involved in cholesterol transport.

Pub. Date : 2011

PMID : 21931618






1 Functional Relationships(s)
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1 Treatment of fibroblasts with cyclopamine, an antagonist of Shh signaling, inhibits Patched expression and reduces BODIPY-cholesterol efflux, while treatment with the Shh pathway agonist SAG enhances Patched protein expression and BODIPY-cholesterol efflux. cyclopamine sonic hedgehog Mus musculus