Title : Thr302 is the site for the covalent modification of human cytochrome P450 2B6 leading to mechanism-based inactivation by tert-butylphenylacetylene.

Pub. Date : 2011 Dec

PMID : 21930824






1 Functional Relationships(s)
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1 Unlike CYP2B1 and CYP2B4, in addition to the formation of an apoprotein adduct and a glutathione conjugate, a small heme adduct was observed when CYP2B6 was incubated with BPA. Heme cytochrome P450 family 2 subfamily B member 6 Homo sapiens