Title : Francisella tularensis reveals a disparity between human and mouse NLRP3 inflammasome activation.

Pub. Date : 2011 Nov 11

PMID : 21930705






1 Functional Relationships(s)
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1 In addition, inhibitors of reactive oxygen species, cathepsin B, and K(+) efflux pathways, known to specifically influence NLRP3, substantially but not completely impair the Francisella-elicited IL-1beta response, suggesting the involvement of another inflammasome pathway. Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens