Pub. Date : 2011 Nov 4
PMID : 21921033
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We find that the MAP 3-kinase MEKK1 acts as a novel TTP kinase that, together with the TNF receptor-associated factor 2 (TRAF2), constitutes not only a main determinate of the NF-kappaB-JNK cross-talk but also facilitates "TTP hypermodification": MEKK1 triggers TTP phosphorylation as prerequisite for its Lys-63-linked, TRAF2-mediated ubiquitination. | Lysine | mitogen-activated protein kinase 8 | Homo sapiens |