Title : Alcohol metabolism in human cells causes DNA damage and activates the Fanconi anemia-breast cancer susceptibility (FA-BRCA) DNA damage response network.

Pub. Date : 2011 Dec

PMID : 21919919






2 Functional Relationships(s)
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1 RESULTS: Incubation of HeLa-ADH1B cells with ethanol (20 mM) resulted in acetaldehyde accumulation in the media, which was prevented by co-incubation with 4-methyl pyrazole (4-MP), a specific inhibitor of ADH. Fomepizole alcohol dehydrogenase 1B (class I), beta polypeptide Homo sapiens
2 RESULTS: Incubation of HeLa-ADH1B cells with ethanol (20 mM) resulted in acetaldehyde accumulation in the media, which was prevented by co-incubation with 4-methyl pyrazole (4-MP), a specific inhibitor of ADH. Fomepizole alcohol dehydrogenase 1B (class I), beta polypeptide Homo sapiens