Pub. Date : 2011 Nov
PMID : 21909943
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In accordance with previous results in breast cancer cells (Choi et al., 2010), the knockdown of GIPC reduced ROS production in response to IGF-1 in colon cancer cells. | Reactive Oxygen Species | GIPC PDZ domain containing family member 1 | Homo sapiens |
2 | Taken together, these data suggest that GIPC is involved in IGF-1 signaling leading to ZNF143 expression through the regulation of ROS production, which may play a role for colon cancer tumorigenesis. | Reactive Oxygen Species | GIPC PDZ domain containing family member 1 | Homo sapiens |