Title : GAIP-interacting protein, C-terminus is involved in the induction of zinc-finger protein 143 in response to insulin-like growth factor-1 in colon cancer cells.

Pub. Date : 2011 Nov

PMID : 21909943






2 Functional Relationships(s)
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1 In accordance with previous results in breast cancer cells (Choi et al., 2010), the knockdown of GIPC reduced ROS production in response to IGF-1 in colon cancer cells. Reactive Oxygen Species GIPC PDZ domain containing family member 1 Homo sapiens
2 Taken together, these data suggest that GIPC is involved in IGF-1 signaling leading to ZNF143 expression through the regulation of ROS production, which may play a role for colon cancer tumorigenesis. Reactive Oxygen Species GIPC PDZ domain containing family member 1 Homo sapiens