Pub. Date : 2011 Nov
PMID : 21908593
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The C. albicans autoregulatory molecule, farnesol, inhibits Ras1 signaling through adenylate cyclase and bears structural similarities to the farnesyl molecule that modifies Ras1. | Farnesol | Ras family GTPase RAS1 | Saccharomyces cerevisiae S288C |
| 2 | The C. albicans autoregulatory molecule, farnesol, inhibits Ras1 signaling through adenylate cyclase and bears structural similarities to the farnesyl molecule that modifies Ras1. | Farnesol | Ras family GTPase RAS1 | Saccharomyces cerevisiae S288C |
| 3 | At lower concentrations of farnesol, hyphal growth was inhibited but Ras1 plasma membrane association was not altered; higher concentrations of farnesol led to mislocalization of Ras1 and another G protein, Rac1. | Farnesol | Ras family GTPase RAS1 | Saccharomyces cerevisiae S288C |
| 4 | Furthermore, farnesol inhibited hyphal growth mediated by cytosolic Ras1-C288SG13V, suggesting that farnesol does not act through mechanisms that depend on Ras1 farnesylation. | Farnesol | Ras family GTPase RAS1 | Saccharomyces cerevisiae S288C |