Title : Etoposide-mediated glioblastoma cell death: dependent or independent on the expression of its target, topoisomerase II alpha?

Pub. Date : 2011 Nov

PMID : 21904904






1 Functional Relationships(s)
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1 CONCLUSIONS: In vitro, the levels of TopoIIa protein expression correlate with response to etoposide but also multiple molecular events namely DNA-PK and MDR also play a role in cell sensitivity to etoposide. Etoposide protein kinase, DNA-activated, catalytic subunit Homo sapiens