Title : Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca2+ release channel by NADPH oxidase 4.

Pub. Date : 2011 Sep 20

PMID : 21896730






1 Functional Relationships(s)
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1 Thus, Nox4 is an O(2) sensor in skeletal muscle, and O(2)-coupled hydrogen peroxide production by Nox4 governs the redox state of regulatory RyR1 thiols and thereby governs muscle performance. Hydrogen Peroxide ryanodine receptor 1 Homo sapiens