Pub. Date : 2011 Dec
PMID : 21896339
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Prevention of FGF-2-induced angiogenesis by scopoletin, a coumarin compound isolated from Erycibe obtusifolia Benth, and its mechanism of action. | Scopoletin | fibroblast growth factor 2 | Homo sapiens |
2 | As to human umbilical vein endothelial cells (HUVECs), scopoletin could inhibit their proliferation, migration and tubule formation induced by FGF-2, especially the proliferation. | Scopoletin | fibroblast growth factor 2 | Homo sapiens |
3 | These findings suggest that scopoletin is substantially able to attenuate FGF-2-induced angiogenesis, and it might act by directly preventing the stimulation action of FGF-2 and by indirectly decreasing the production of VEGF. | Scopoletin | fibroblast growth factor 2 | Homo sapiens |
4 | These findings suggest that scopoletin is substantially able to attenuate FGF-2-induced angiogenesis, and it might act by directly preventing the stimulation action of FGF-2 and by indirectly decreasing the production of VEGF. | Scopoletin | fibroblast growth factor 2 | Homo sapiens |