Title : Macrophage colony stimulating factor regulation by nuclear factor kappa B: a relevant pathway in human immunodeficiency virus type 1 infected macrophages.

Pub. Date : 2012 Mar

PMID : 21895511






2 Functional Relationships(s)
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1 TNF-alpha treatment promoted NF-kappaB p65 binding to the M-CSF promoter in phorbol 12-myristate 13-acetate (PMA) treated U937 cells chronically infected with HIV-1 (U1 cells), but not in PMA treated uninfected U937 cells, suggesting that the presence of HIV-1 increases the NF-kappaB response. Tetradecanoylphorbol Acetate RELA proto-oncogene, NF-kB subunit Homo sapiens
2 TNF-alpha treatment promoted NF-kappaB p65 binding to the M-CSF promoter in phorbol 12-myristate 13-acetate (PMA) treated U937 cells chronically infected with HIV-1 (U1 cells), but not in PMA treated uninfected U937 cells, suggesting that the presence of HIV-1 increases the NF-kappaB response. Tetradecanoylphorbol Acetate RELA proto-oncogene, NF-kB subunit Homo sapiens