Pub. Date : 2011 Aug 11
PMID : 21892977
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rationales for use of vasopressin in septic shock are as follows: first, a deficiency of vasopressin in septic shock; second, low-dose vasopressin infusion improves blood pressure, decreases requirements for norepinephrine and improves renal function; and third, a recent randomized, controlled, concealed trial of vasopressin versus norepinephrine (VASST) suggests low-dose vasopressin may decrease mortality of less severe septic shock. | Norepinephrine | arginine vasopressin | Homo sapiens |
| 2 | Rationales for use of vasopressin in septic shock are as follows: first, a deficiency of vasopressin in septic shock; second, low-dose vasopressin infusion improves blood pressure, decreases requirements for norepinephrine and improves renal function; and third, a recent randomized, controlled, concealed trial of vasopressin versus norepinephrine (VASST) suggests low-dose vasopressin may decrease mortality of less severe septic shock. | Norepinephrine | arginine vasopressin | Homo sapiens |
| 3 | There was potential benefit in the prospectively defined stratum of patients with less severe septic shock (5 to 14 mug/minute norepinephrine at randomization): vasopressin may have lowered mortality compared with norepinephrine (26% versus 36%, respectively, P = 0.04 within stratum). | Norepinephrine | arginine vasopressin | Homo sapiens |
| 4 | In conclusion, low-dose vasopressin may be effective in patients who have less severe septic shock already receiving norepinephrine (such as patients with modest norepinephrine infusion (5 to 15 mug/minute) or low serum lactate levels). | Norepinephrine | arginine vasopressin | Homo sapiens |
| 5 | In conclusion, low-dose vasopressin may be effective in patients who have less severe septic shock already receiving norepinephrine (such as patients with modest norepinephrine infusion (5 to 15 mug/minute) or low serum lactate levels). | Norepinephrine | arginine vasopressin | Homo sapiens |