Pub. Date : 2011 Sep
PMID : 21892192
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of the histamine H(1) receptor antagonist hydroxyzine on hERG K(+) channels and cardiac action potential duration. | Hydroxyzine | ETS transcription factor ERG | Homo sapiens |
| 2 | AIM: To investigate the effects of hydroxyzine on human ether-a-go-go-related gene (hERG) channels to determine the electrolphysiological basis for its proarrhythmic effects. | Hydroxyzine | ETS transcription factor ERG | Homo sapiens |
| 3 | Hydroxyzine (0.03-3 mumol/L) blocked both the steady-state and tail hERG currents. | Hydroxyzine | ETS transcription factor ERG | Homo sapiens |
| 4 | CONCLUSION: The results suggest that hydroxyzine could block hERG channels and prolong APD. | Hydroxyzine | ETS transcription factor ERG | Homo sapiens |