Pub. Date : 1990 Jun 1
PMID : 2188736
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Recombinant human ras p21 GAP (GTPase activating protein) at subnanomolar concentrations inhibited GTP-dependent channel opening in isolated atrial cell membranes. | Guanosine Triphosphate | H3 histone pseudogene 16 | Homo sapiens |
| 2 | We therefore propose that ras p21 GTP complexed with GAP (ras p21-GAP) blocks K+[ACh] currents. | Guanosine Triphosphate | H3 histone pseudogene 16 | Homo sapiens |
| 3 | We therefore propose that ras p21 GTP complexed with GAP (ras p21-GAP) blocks K+[ACh] currents. | Guanosine Triphosphate | H3 histone pseudogene 16 | Homo sapiens |
| 4 | The channel block could be overcome by GTP gamma S activation of endogenous Gk; this indicates that ras p21-GAP does not interfere with interaction of Gk with the K+[ACh] channel directly, but prevents coupling of the muscarinic receptor to endogenous Gk. | Guanosine Triphosphate | H3 histone pseudogene 16 | Homo sapiens |