Pub. Date : 2011 Nov 3
PMID : 21881044
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, as one remarkable example, studies using a novel and highly selective pharmacologic inhibitor of the spleen tyrosine kinase Syk [PRT060318; 2-((1R,2S)-2-aminocyclohexylamino)-4-(m-tolylamino)pyrimidine-5-carboxamide] coupled with genetic experiments, demonstrate that Syk inhibition ameliorates both the acute and chronic responses to vascular injury without affecting hemostasis. | 2-(2-aminocyclohexylamino)-4-(m-tolylamino)pyrimidine-5-carboxamide | spleen tyrosine kinase | Mus musculus |
| 2 | Here, as one remarkable example, studies using a novel and highly selective pharmacologic inhibitor of the spleen tyrosine kinase Syk [PRT060318; 2-((1R,2S)-2-aminocyclohexylamino)-4-(m-tolylamino)pyrimidine-5-carboxamide] coupled with genetic experiments, demonstrate that Syk inhibition ameliorates both the acute and chronic responses to vascular injury without affecting hemostasis. | 2-(2-aminocyclohexylamino)-4-(m-tolylamino)pyrimidine-5-carboxamide | spleen tyrosine kinase | Mus musculus |