Title : [Epilepsy and pro-inflammatory cytokines. Immunomodulating properties of antiepileptic drugs].

Pub. Date : 2011 May-Jun

PMID : 21866484






2 Functional Relationships(s)
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1 In vitro and in vivo experiments show that antiepileptic drugs could affect cytokine levels (e.g. valproate significantly inhibited production of TNF- alpha and IL-6 by human monocytic leukaemia cells). Valproic Acid tumor necrosis factor Homo sapiens
2 In epilepsy patients studies (including ex vivo) show elevated levels of IL-1 beta, IL-2, IL-5, IL-6 or TNF- alpha after carbamazepine, valproic acid and phenytoin. Valproic Acid tumor necrosis factor Homo sapiens