Title : Genome-wide expression profiling and mutagenesis studies reveal that lipopolysaccharide responsiveness appears to be absolutely dependent on TLR4 and MD-2 expression and is dependent upon intermolecular ionic interactions.

Pub. Date : 2011 Oct 1

PMID : 21865549






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 However, the MyD88-dependent and -independent pathways were impaired to the same extent, indicating that the adjuvant activity of monophosphorylated lipid A most likely arises from its decreased potential to induce an active receptor complex and not more downstream signaling events. Lipid A myeloid differentiation primary response gene 88 Mus musculus