Title : Basis for half-site ligand binding in yeast NAD(+)-specific isocitrate dehydrogenase.

Pub. Date : 2011 Sep 27

PMID : 21861471






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A tetrameric form of IDH (an IDH1(G15D)/IDH2 mutant enzyme) demonstrated half-site binding for isocitrate (two sites) in the absence of dithiothreitol and full-site binding (four sites) in the presence of dithiothreitol. isocitric acid isocitrate dehydrogenase (NAD(+)) IDH2 Saccharomyces cerevisiae S288C