Title : Inhibition of chronic pancreatitis and pancreatic intraepithelial neoplasia (PanIN) by capsaicin in LSL-KrasG12D/Pdx1-Cre mice.

Pub. Date : 2011 Nov

PMID : 21859833






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In the present study, the effect of capsaicin on pancreatitis and pancreatic intraepithelial neoplasia (PanIN) was determined in a mutant Kras-driven and caerulein-induced pancreatitis-associated carcinogenesis in LSL-Kras(G12D)/Pdx1-Cre mice. Capsaicin Kirsten rat sarcoma viral oncogene homolog Mus musculus
2 These results indicate that capsaicin could be a promising agent for the chemoprevention of pancreatic carcinogenesis, possibly via inhibiting pancreatitis and mutant Kras-led ERK activation. Capsaicin Kirsten rat sarcoma viral oncogene homolog Mus musculus