Title : Nuclear proteome analysis reveals a role of Vav1 in modulating RNA processing during maturation of tumoral promyelocytes.

Pub. Date : 2011 Dec 21

PMID : 21856460






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Vav1 is a key molecule in the ATRA-induced acquisition of a mature phenotype by tumoral myeloid precursors. Tretinoin vav guanine nucleotide exchange factor 1 Homo sapiens
2 The obtained data demonstrated that, in NB4 cells treated with ATRA, Vav1 is involved in determining the nuclear amount of proteins involved in molecular complexes with DNA and may participate to RNA processing by carrying in the nucleus molecules involved in modulating mRNA production and stability, like hnRNPs and SR proteins. Tretinoin vav guanine nucleotide exchange factor 1 Homo sapiens