Title : Plasmodium falciparum: effect of antimalarial drugs, malaria pigment (β-haematin) and Plasmodium falciparum lysate on monocyte GTP-cyclohydrolase 1 gene expression.

Pub. Date : 2011 Nov

PMID : 21854775






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In interferon-gamma activated human macrophages, GTP-cyclohydrolase 1 catalyses the conversion of guanosine triphosphate to 7,8-dihydroneopterin triphosphate, which is dephosphorylated and oxidized to form neopterin. Neopterin interferon gamma Homo sapiens