Title : The transformed glucocorticoid receptor has a lower steroid-binding affinity than the nontransformed receptor.

Pub. Date : 1990 Feb 20

PMID : 2184891






4 Functional Relationships(s)
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1 The transformed glucocorticoid receptor has a lower steroid-binding affinity than the nontransformed receptor. Steroids nuclear receptor subfamily 3 group C member 1 Homo sapiens
2 High-salt treatment of cytosolic glucocorticoid receptor (GR) preparations reduces the steroid-binding ability of the receptor and induces the conversion of the receptor from a nontransformed (non-DNA-binding) 9S form to a transformed (DNA-binding) 4S entity. Steroids nuclear receptor subfamily 3 group C member 1 Homo sapiens
3 High-salt treatment of cytosolic glucocorticoid receptor (GR) preparations reduces the steroid-binding ability of the receptor and induces the conversion of the receptor from a nontransformed (non-DNA-binding) 9S form to a transformed (DNA-binding) 4S entity. Steroids nuclear receptor subfamily 3 group C member 1 Homo sapiens
4 Steroid-free GR was converted from a 9S to a 4S form by exposure to 0.4 M NaCl. Steroids nuclear receptor subfamily 3 group C member 1 Homo sapiens