Title : Influence of C-terminal α-helix hydrophobicity and aromatic amino acid content on apolipoprotein A-I functionality.

Pub. Date : 2012 Mar

PMID : 21840419






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 With apoA-I (F225L/F229L/A232L/Y236L) where the hydrophobicity is restored by the presence of only leucine residues in the helix non-polar face, the catalytic efficiencies of vesicle solubilization and cholesterol efflux are similar to those of WT apoA-I; this variant forms smaller HDL particles. Leucine apolipoprotein A1 Homo sapiens