Pub. Date : 2011 Dec
PMID : 21833471
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | It was found that the cell line, called Tumor2 with down-regulation of basal ROS and manganese superoxide dismutase (MnSOD) expression as a constitutive pattern of this cell line, presented alterations in genes that confer metastatic potential in comparison to the Alpha5 cell line, showing overexpression of basal MnSOD and high levels of ROS. | Reactive Oxygen Species | superoxide dismutase 2 | Homo sapiens |
| 2 | Interesting, it was to found that CD44, considered a metastatic suppressor gene, was influenced by ROS, measured by hydrogen peroxide treatments, as seen by decreased CD44 protein expression in the Alpha5 cell line in a compensatory response to increased MnSOD protein expression. | Reactive Oxygen Species | superoxide dismutase 2 | Homo sapiens |