Title : Identification of the rate-determining process in the hepatic clearance of atorvastatin in a clinical cassette microdosing study.

Pub. Date : 2011 Oct

PMID : 21832990






1 Functional Relationships(s)
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1 The pharmacokinetics of this cocktail was observed at baseline, after an oral dose of 600 mg rifampicin (an inhibitor of OATPs), and after an intravenous dose of 200 mg itraconazole (a CYP3A4 inhibitor). Itraconazole cytochrome P450 family 3 subfamily A member 4 Homo sapiens