Title : Luciferin IPA-based higher throughput human hepatocyte screening assays for CYP3A4 inhibition and induction.

Pub. Date : 2011 Sep

PMID : 21832258






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In the 96-well plate induction assay, the CYP3A4 inducers rifampin, phenobarbital, carbamazepine, phenytoin, troglitazone, rosiglitazone, and pioglitazone yielded dose-dependent induction of LIPA metabolism, whereas the CYP1A2 inducers omeprazole and 3-methylcholanthrene did not display any induction in the CYP3A4 activity. Phenobarbital cytochrome P450 family 3 subfamily A member 4 Homo sapiens