Title : Adiponectin upregulates prolyl-4-hydroxylase α1 expression in interleukin 6-stimulated human aortic smooth muscle cells by regulating ERK 1/2 and Sp1.

Pub. Date : 2011

PMID : 21829524






2 Functional Relationships(s)
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Protein Name
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1 Adiponectin significantly increased P4Halpha1 mRNA and protein levels in IL-6-stimulated HASMCs in a dose- and time-dependent manner. hasmcs interleukin 6 Homo sapiens
2 As well, ERK1/2 and Sp1 played a crucial role in the effect of adiponectin upregulating P4Halpha1 expression in IL-6-stimulated HASMCs. hasmcs interleukin 6 Homo sapiens