Title : Dietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase IIα.

Pub. Date : 2011 Sep 23

PMID : 21828038






4 Functional Relationships(s)
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1 In addition, proteomic analysis revealed that several cysteine residues on human Top2alpha were covalently modified by benzyl-ITC, suggesting that ITC-induced Top2alpha cleavage complexes may involve cysteine modification. Cysteine DNA topoisomerase II alpha Homo sapiens
2 In addition, proteomic analysis revealed that several cysteine residues on human Top2alpha were covalently modified by benzyl-ITC, suggesting that ITC-induced Top2alpha cleavage complexes may involve cysteine modification. Cysteine DNA topoisomerase II alpha Homo sapiens
3 In addition, proteomic analysis revealed that several cysteine residues on human Top2alpha were covalently modified by benzyl-ITC, suggesting that ITC-induced Top2alpha cleavage complexes may involve cysteine modification. Cysteine DNA topoisomerase II alpha Homo sapiens
4 In addition, proteomic analysis revealed that several cysteine residues on human Top2alpha were covalently modified by benzyl-ITC, suggesting that ITC-induced Top2alpha cleavage complexes may involve cysteine modification. Cysteine DNA topoisomerase II alpha Homo sapiens