Title : Pyridoxal 5'-phosphate-dependent histidine decarboxylase. Mechanism of inactivation by alpha-fluoromethylhistidine.

Pub. Date : 1990 Apr 25

PMID : 2182624






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A mutant histidine decarboxylase (S322A) in which Ser-322 was changed to Ala was also inactivated by alpha-fluoromethylhistidine demonstrating that Ser-322 is not essential for inactivation even though it is close to the active site and is derivatized by borohydride reduction of the inactivated wild-type enzyme. Borohydrides histidine decarboxylase Homo sapiens