Title : Activation of mitogen-activated protein kinases by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) plays an important role in macrophage stimulation.

Pub. Date : 2011 Nov 1

PMID : 21819972






1 Functional Relationships(s)
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1 By using selective inhibitors of MAPKs, this study confirms that both activated p38/MK2 pathways and ERK1/2 MAPK play a significant role in regulation of both TNF-alpha and IL-6 protein production induced by DMXAA at the post-transcriptional level. vadimezan interleukin 6 Mus musculus