Title : Contact sensitizers modulate the arachidonic acid metabolism of PMA-differentiated U-937 monocytic cells activated by LPS.

Pub. Date : 2011 Oct 1

PMID : 21807015






1 Functional Relationships(s)
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1 Our results showed that among the tested molecules, all sensitizers specifically prevent the production of PMA/LPS-induced COX-2 metabolites (PGE(2,) TxB(2) and PGD(2)), eugenol and cinnamaldehyde inhibiting also the production of IL-1beta and TNF-alpha. Tetradecanoylphorbol Acetate mitochondrially encoded cytochrome c oxidase II Homo sapiens