Pub. Date : 2011 Jul 31
PMID : 21801448
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Finally, the caspase-9 inhibitor Ac-LEHD-CHO or caspase-9 siRNA blocked etoposide-induced caspase-8 activation, Bid cleavage, and apoptosis in both cell lines, indicating that p53/p73-dependent caspase-8 activation lies downstream of mitochondria. | Etoposide | caspase 9 | Homo sapiens |
2 | Finally, the caspase-9 inhibitor Ac-LEHD-CHO or caspase-9 siRNA blocked etoposide-induced caspase-8 activation, Bid cleavage, and apoptosis in both cell lines, indicating that p53/p73-dependent caspase-8 activation lies downstream of mitochondria. | Etoposide | caspase 9 | Homo sapiens |