Title : [Effect of cholesterol on the functional activity of proteins responsible for the resistance of human lymphocytes to xenobiotics].

Pub. Date : 2011 May-Jun

PMID : 21786699






8 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The influence of agents modifying cholesterol in plasma membranes on the functional activity of transporter proteins (P-glycoprotein (P-gp) and the multidrug resistance protein 1 (MRP1)) in human lymphocytes has been studied. Cholesterol ATP binding cassette subfamily B member 1 Homo sapiens
2 The influence of agents modifying cholesterol in plasma membranes on the functional activity of transporter proteins (P-glycoprotein (P-gp) and the multidrug resistance protein 1 (MRP1)) in human lymphocytes has been studied. Cholesterol ATP binding cassette subfamily B member 1 Homo sapiens
3 It was shown that changes in lateral distribution of cholesterol using the polyene antibiotic filipin, which disturb the structure and function of glycolipid microdomains in plasma membranes of lymphocytes lead to a decrease in the transport activity of both P-gp and MRP1. Cholesterol ATP binding cassette subfamily B member 1 Homo sapiens
4 It was shown that changes in lateral distribution of cholesterol using the polyene antibiotic filipin, which disturb the structure and function of glycolipid microdomains in plasma membranes of lymphocytes lead to a decrease in the transport activity of both P-gp and MRP1. Cholesterol ATP binding cassette subfamily B member 1 Homo sapiens
5 It was concluded that the transport activity of P-gp and MRP1 depends on the modification of cholesterol in the membranes of human lymphocytes, i.e., is closely associated with the level of cholesterol and its lateral distribution. Cholesterol ATP binding cassette subfamily B member 1 Homo sapiens
6 It was concluded that the transport activity of P-gp and MRP1 depends on the modification of cholesterol in the membranes of human lymphocytes, i.e., is closely associated with the level of cholesterol and its lateral distribution. Cholesterol ATP binding cassette subfamily B member 1 Homo sapiens
7 It was concluded that the transport activity of P-gp and MRP1 depends on the modification of cholesterol in the membranes of human lymphocytes, i.e., is closely associated with the level of cholesterol and its lateral distribution. Cholesterol ATP binding cassette subfamily B member 1 Homo sapiens
8 It was concluded that the transport activity of P-gp and MRP1 depends on the modification of cholesterol in the membranes of human lymphocytes, i.e., is closely associated with the level of cholesterol and its lateral distribution. Cholesterol ATP binding cassette subfamily B member 1 Homo sapiens